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Methods: In this study, the patients with mild to moderate acne vulgaris were divided into two groups, one group was treated with topical adapalene whereas topical benzoyl peroxide-clindamycin combination was given to the other group. Assessment of efficacy was done by total lesion counting while safety assessment was done by noting the adverse drug reactions due to medication, the results were compared at the end of 1, 2 and 3 months with the baseline values.

The tolerability profile of adapalene was comparatively better than benzoyl peroxide-clindamycin combination. Conclusions: Adapalene is as efficacious as benzoyl peroxide-clindamycin combination to treat mild to moderate acne vulgaris, but it is comparatively better tolerated than benzoyl peroxide-clindamycin combination.

Emil A. The role of inflammation in the pathology of acne. J Clin Aesthet Dermatol. Comparison of clinical efficacy of topical clindamycin with adapalene and adapalene alone in treatment of mild to moderate facial acne vulgaris.

Int J Pharm Bio Sci. Dutil M. Benzoyl peroxide: enhancing antibiotic efficacy in acne management. Skin Therapy Lett. Persy SH. Safety and efficacy of adapalene gel 0. Indian J Dermatol Venereol Leprol.

Scoring systems in acne vulgaris. Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: a randomized controlled trial.

Indian J Pharmacol. Adapalene pretreatment increases follicular penetration of clindamycin: In vitro and in vivo studies. Efficacy and safety of a nano-emulsion gel formulation of adapalene 0. Indian J Dermatolo Venereol Leprol.

Randomised, controlled trial of the efficacy and safety of adapalene gel 0. Eur J Dermatol. Comparative irritancy study among retinoid creams and gels. J Cutan Med Surg. Randomized, controlled, bilateral split-face comparison trial of the tolerability and patient preference of adapalene gel 0.

Topical adapalene gel 0. Br J Dermatol.

 

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Eligible for Free Shipping. Customer Reviews. Skin Cleaning Agent Scent. Skin Cleaning Agent Special Ingredients. Skin Cleanser Material Free. Skin Cleaning Agent Product Benefits. Skin Cleanser Material Features. Subscription Options. International Shipping. Your recently viewed items and featured recommendations. Back to top. Get to Know Us. Make Money with Us. Amazon Payment Products. Let Us Help You. Amazon Music Stream millions of songs. Amazon Advertising Find, attract, and engage customers.

Amazon Drive Cloud storage from Amazon. Sell on Amazon Start a Selling Account. AmazonGlobal Ship Orders Internationally. ComiXology Thousands of Digital Comics. DPReview Digital Photography. Shopbop Designer Fashion Brands. Deals and Shenanigans. Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: a randomized controlled trial. Indian J Pharmacol. Adapalene pretreatment increases follicular penetration of clindamycin: In vitro and in vivo studies.

Efficacy and safety of a nano-emulsion gel formulation of adapalene 0. Indian J Dermatolo Venereol Leprol. Randomised, controlled trial of the efficacy and safety of adapalene gel 0. Eur J Dermatol. Comparative irritancy study among retinoid creams and gels. J Cutan Med Surg. Randomized, controlled, bilateral split-face comparison trial of the tolerability and patient preference of adapalene gel 0. Topical adapalene gel 0.

Br J Dermatol. Comparative evaluation of effectiveness of adapalene and azithromycin, alone or in combination, in acne vulgaris. Indian J Dermatol. User Username Password Remember me. Font Size. Notifications View Subscribe. Article Tools Print this article. Indexing metadata.

How to cite item. Finding References. Email this article Login required. Comparison of efficacy and safety of adapalene and benzoyl peroxide-clindamycin combination in the topical treatment of acne vulgaris. Abstract Background: Acne vulgaris is a dermatological disorder characterised by formation of comedones and inflammatory lesions. Keywords Pilo-sebaceous unit, Comedones, Antimicrobials, Retinoids. Full Text: PDF. References Emil A. Selway J.